General Western Blot Reagents
Abcam Oligomycin A, ATP synthase inhibitor, 1MG
MW 791.1 Da, Purity >97%. Macrolide antibiotic. ATP synthase inhibitor. Blocks the proton channel (Fo subunit) to uncouple oxidative phosphorylation. Shows antitumor activity. Active in vivo.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Oligomycin A, ATP synthase inhibitor, 5MG
MW 791.1 Da, Purity >97%. Macrolide antibiotic. ATP synthase inhibitor. Blocks the proton channel (Fo subunit) to uncouple oxidative phosphorylation. Shows antitumor activity. Active in vivo.
The product is subject to the following: Abcam Restricted Use Statement
Abcam WY 14643, PPARalpha agonist, 50MG
MW 323.8 g/mol, Purity >99%. Selective PPARα agonist (EC₅₀ values are 0.63, 32 and >100 μM at PPARα, PPARγ and PPARδ receptors respectively). Able to reduce inflammatory responses in vivo and in vitro.
The product is subject to the following: Abcam Restricted Use Statement
Abcam SMI-4a, ATP-competitive Pim kinase inhibitor, 5MG
MW 273.23 Da. Potent, selective, cell-permeable, ATP-competitive Pim-1 kinase inhibitor (IC₅₀ = 17 nM). Moderately potent against Pim-2 kinase. Selective versus a panel of other serine/threonine and tyrosine kinases. Inhibits the growth of myeloid and lymphoid cell lines. Induces cell cycle arrest in leukemia and prostate cancer cells.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Betamethasone valerate, Glucocorticoid; immunomodulator, 100MG
MW 476.6 Da, Purity >98%. Glucocorticoid. Major steroid hormone. Anti-inflammatory and immunosuppresive effects. Active in vivo.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Troglitazone, PPAR-gamma receptor agonist, 10MG
MW 441.5 Da, Purity >97%. Potent, selective PPAR-γ receptor agonist (EC₅₀ = 780 nM). No activity at PPAR-α or PPAR-δ (up to 10 mM). Orally active. Antidiabetic and anticancer agent. Active in vivo and in vitro.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Neuromedin B (porcine), Bombesin-like peptide, 1MG
MW 1132.3 Da, Purity >90%. Neuromedin B (porcine), Bombesin-like peptide. Achieve your results faster with highly validated, pure and trusted compounds.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Dienogest, Steroidal progesterone, 25MG
MW 311.4 Da, Purity >99%. Steroidal progesterone. Non-ethinylated progestin structurally related to testosterone. Anti-androgenic and antiproliferative effects in vitro.
The product is subject to the following: Abcam Restricted Use Statement
Sigma Aldrich Fine Chemicals Biosciences Q SepharoseR Fast Flow Cyt
Q Sepharose(R) Fast Flow is a strong anion exchanger based on the well established Sepharose(R) Fast Flow ion exchange platform extensively used for preparative protein separations in both research and industrial applications.Q Sepharose(R) Fast Flow is part of the Sepharose(R) Fast Flow ion exchange platform which has been the industrial standard for ion exchange chromatography during recent decades. It is composed of crosslinked 6% agarose beads with quaternary ammonium (Q) strong anion exchange groups. Q Sepharose(R) Fast Flow has high chemical stability allowing well proven cleaning-in-place (CIP) and sanitization protocols. Scale-up with Q Sepharose(R) Fast Flow is straight forward and the medium is available in a range of pre-packed process development tools.As member of the BioProcess media range Q Sepharose(R) Fast Flow meets industrial demands with security of supply and comprehensive technical and regulatory support.
Abcam Marimastat, Matri x metalloprotease (MMP) inhibitor, 10MG
MW 331.41 Da, Purity >98%. Potent matrix metalloproteinase inhibitor. Broad-spectrum inhibitor of all major MMPs. Prevents or reduces spread and growth of tumors.
The product is subject to the following: Abcam Restricted Use Statement
Abcam AMI 1, protein arginine methyltransferase inhibitor, 25MG
MW 548.5 Da, Purity =99%. Potent, selective and reversible protein arginine methyltransferase inhibitor (IC₅₀ = 1.63 μM). ROS° scavenger with antioxidant effects (IC₅₀ = 8.3 μM). Inhibits arginine in vitro without competing for the AdoMet binding site. Modulates nuclear receptor-regulated transcription in vivo. Cell-permeable.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Melatonin, Endogenous hormone agonist at MT1 and MT2 receptors, 50MG
MW 232.28 Da, Purity >99%. Agonist at melatonin MT1 and MT2 receptors. Endogenous hormone important in the control of the circadian rhythm. Wide range of pathophysiological functions including antioxidative and immunomodulatory effects.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Progesterone, Endogenous progesterone receptor agonist, 100MG
MW 314.5 Da, Purity >99%. Endogenous progesterone receptor agonist (EC₅₀ = 0.5 nM) C-21 steroid hormone. Elicits a variety of biological effects.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Auranofin, inhibits both leukocyte activation pathways, 50MG
MW 678.5 Da, Purity >98%. Organic gold compound. Anti-inflammatory and antiproliferative agent. Glutathione S-transferase P1-1 inhibitor (IC50 = 33 μM). Shows antiproliferative effects through STAT3 inhibition. Shows anti-inflammatory effects *in vivo*. Orally active.
The product is subject to the following: Abcam Restricted Use Statement
Abcam AM 80, retinoic acid receptor alpha/beta (RAR alpha/beta) agonist, 50MG
MW 351.44 g/mol, Purity >98%. Selective retinoic acid receptor α/β (RARα/β) agonist. Induces differentiation and anti-cancer activity in vivo and in vitro.
The product is subject to the following: Abcam Restricted Use Statement